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Description & Usage

Proin Chewables for Dogs work by increasing urethral sphincter muscle tone to help prevent urinary incontinence (urethral sphincter hypotonus). Proin is an FDA approved prescription medication. The scored tablets available in three strenths allow for precise dosing. These liver flavored chewables are loved by all dogs and easy to administer. 

Precautions & Side Effects

Not for human use. Keep out of reach of children. Keep Proin in a secured location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose. Proin may cause increased thirst; therefore, always provide ample fresh water when administering the tablets. It may take several days of treatment with Proin before urinary incontinence improves.

Always follow the dosage instructions provided by your veterinarian. Monitor your dog after giving Proin to be sure all of it was consumed.  

Overdose has been associated with dogs chewing through closed bottles of PROIN and consuming multiple tablets. Therefore, it is important to store PROIN Chewable Tablets out of reach of dogs and other pets in a secured location.

Proin may cause hypertension; therefore, use with caution in dogs with pre-existing heart disease, hypertension, liver disease, kidney insufficiency, diabetes, glaucoma, and conditions with a predilection for hypertension. Use with caution in dogs receiving sympathomimetic drugs, tricyclic antidepressants, or monoamine oxidase inhibitors as increased toxicity may result. Use with caution in dogs administered halogenated gaseous anesthetics as this may increase the risk of cardiac arrhythmias. The safe use of Proin in dogs used for breeding purposes, during pregnancy or in lactating bitches, has not been evaluated.

Active Ingredient: Phenylpropanolamine


Administer the chewable tablet by mouth daily as recommended by your veterinarian. Always provide fresh water and make sure the tablet is entirely consumed by your dog. 


The total recommended dosage for oral administration is 2 mg/kg (0.91 mg/lb) of body weight twice daily. Proin is scored and dosage should be calculated in halftablet increments.


Store at controlled room temperature 20-25°C (68-77°F), excursions permitted between 15-40°C (59-104°F)

What are the signs of urinary incontinence in dogs?

• Dripping or leaking urine

• Excessive licking of genital area

• Red, irritated skin around genital area

• Increased frequency of need to urinate

• Wetting the bed or sleeping area

• Inappropriate urination in the house